Article
Functional SNP in stem of mir-146a affects Her2 status and breast cancer survival.
Cancer biomarkers : section A of Disease markers - 8 Jul 2016
Meshkat Mahboobeh, Tanha Hamzeh Mesrian, Naeini Marjan Mojtabavi, Ghaedi Kamran, Sanati Mohammad H, Meshkat Marzieh, Bagheri Fatemeh
Abstract excerpt
In-silico investigation suggested a common variant within stem of miR-146a-5p precursor (rs2910164, n.60C>G) associated with breast cancer (BC) phenotypes. Our aim was computationally predicting possible targets of miR-146a-5p and probable rs2910164 mechanism of action in expression of phenotypes in BC. Additionally, a case-control study was designated to examine experimentally the correlation of mir-146a...
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