Article
Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease.
Human genetics - 1 Sept 2008
Keene Keith L, Mychaleckyj Josyf C, Leak Tennille S, Smith Shelly G, Perlegas Peter S, Divers Jasmin, Langefeld Carl D, Freedman Barry I, Bowden Donald W, Sale Michèle M
Abstract excerpt
Admixture and population stratification are major concerns in genetic association studies. We wished to evaluate the impact of admixture using empirically derived data from genetic association studies of African Americans (AA) with type 2 diabetes (T2DM) and end-stage renal disease (ESRD). Seventy ancestry informative markers (AIMs) were genotyped in 577 AA with T2DM-ESRD, 596 AA controls, 44 Yoruba Nigerian...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
