Article
Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND).
BMC genomics - 4 May 2016
Williams Robert C, Elston Robert C, Kumar Pankaj, Knowler William C, Abboud Hanna E, Adler Sharon, Bowden Donald W, Divers Jasmin, Freedman Barry I, Igo Robert P, Ipp Eli, Iyengar Sudha K, Kimmel Paul L, Klag Michael J, Kohn Orly, Langefeld Carl D, Leehey David J, Nelson Robert G, Nicholas Susanne B, Pahl Madeleine V, Parekh Rulan S, Rotter Jerome I, Schelling Jeffrey R, Sedor John R, Shah Vallabh O, Smith Michael W, Taylor Kent D, Thameem Farook, Thornley-Brown Denyse, Winkler Cheryl A, Guo Xiuqing, Zager Phillip, Hanson Robert L
Abstract excerpt
BACKGROUND: The presence of population structure in a sample may confound the search for important genetic loci associated with disease. Our four samples in the Family Investigation of Nephropathy and Diabetes (FIND), European Americans, Mexican Americans, African Americans, and American Indians are part of a genome- wide association study in which population structure might be particularly important. We...
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