Article
A small number of candidate gene SNPs reveal continental ancestry in African Americans.
Annals of human genetics - 1 Jan 2013
Kodaman Nuri, Aldrich Melinda C, Smith Jeffrey R, Signorello Lisa B, Bradley Kevin, Breyer Joan, Cohen Sarah S, Long Jirong, Cai Qiuyin, Giles Justin, Bush William S, Blot William J, Matthews Charles E, Williams Scott M
Abstract excerpt
Using genetic data from an obesity candidate gene study of self-reported African Americans and European Americans, we investigated the number of Ancestry Informative Markers (AIMs) and candidate gene SNPs necessary to infer continental ancestry. Proportions of African and European ancestry were assessed with STRUCTURE (K = 2), using 276 AIMs. These reference values were compared to estimates derived using 120,...
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