Ancestry informative marker panels for African Americans based on subsets of commercially available SNP arrays.

doi:10.1002/gepi.20550

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Article

Ancestry informative marker panels for African Americans based on subsets of commercially available SNP arrays.

Genetic epidemiology - 1 Jan 2011

Tandon Arti, Patterson Nick, Reich David

Abstract excerpt

Admixture mapping is a widely used method for localizing disease genes in African Americans. Most current methods for inferring ancestry at each locus in the genome use a few thousand single nucleotide polymorphisms (SNPs) that are very different in frequency between West Africans and European Americans, and that are required to not be in linkage disequilibrium in the ancestral populations. Modern SNP arrays...

Topics

Black or African American
Black People
Chromosome Mapping
Commerce
Gene Frequency
Genetic Markers
Genetics, Population
Genotype
Humans
Linkage Disequilibrium
Oligonucleotide Array Sequence Analysis
Polymorphism, Single Nucleotide
White People

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Identifiers

PMID: 21181899
DOI: 10.1002/gepi.20550
PMCID: PMC4386999

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