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Article

Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis.

Development (Cambridge, England) - 1 Sept 2008

Chen Yu, Doughman Yong-qiu, Gu Shi, Jarrell Andrew, Aota Shin-ichi, Cvekl Ales, Watanabe Michiko, Dunwoodie Sally L, Johnson Randall S, van Heyningen Veronica, Kleinjan Dirk A, Beebe David C, Yang Yu-Chung

Abstract excerpt

Cited2 is a transcriptional modulator with pivotal roles in different biological processes. Cited2-deficient mouse embryos manifested two major defects in the developing eye. An abnormal corneal-lenticular stalk was characteristic of Cited2(-/-) developing eyes, a feature reminiscent of Peters' anomaly, which can be rescued by increased Pax6 gene dosage in Cited2(-/-) embryonic eyes. In addition, the hyaloid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypoxia-Inducible Factor 1, alpha Subunit

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Source

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Identifiers

PMID: 18653562
DOI: 10.1242/dev.021097
PMCID: PMC2654719

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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