Article
Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice.
PloS one - 23 Jul 2008
Meinzer Ulrich, Esmiol-Welterlin Sophie, Barreau Frederick, Berrebi Dominique, Dussaillant Monique, Bonacorsi Stephane, Chareyre Fabrice, Niwa-Kawakita Michiko, Alberti Corinne, Sterkers Ghislaine, Villard Claude, Lesuffleur Thecla, Peuchmaur Michel, Karin Michael, Eckmann Lars, Giovannini Marco, Ollendorff Vincent, Wolf-Watz Hans, Hugot Jean-Pierre
Abstract excerpt
Nucleotide oligomerisation domain 2 (NOD2) is a component of the innate immunity known to be involved in the homeostasis of Peyer patches (PPs) in mice. However, little is known about its role during gut infection in vivo. Yersinia pseudotuberculosis is an enteropathogen causing gastroenteritis, adenolymphitis and septicaemia which is able to invade its host through PPs. We investigated the role of Nod2 during Y....
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