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Article

ATP negatively regulates the initiator protein of Vibrio cholerae chromosome II replication.

Proceedings of the National Academy of Sciences of the United States of America - 29 Jul 2008

Duigou Stéphane, Yamaichi Yoshiharu, Waldor Matthew K

Abstract excerpt

Vibrio cholerae, the agent of cholera, has two circular chromosomes. In bacteria that contain a single chromosome, initiation of chromosome DNA replication is mediated by DnaA, a AAA+ ATPase that unwinds the origin of replication. There is little knowledge regarding initiation of chromosome replication in bacteria with more than one chromosome. Here, we purified V. cholerae DnaA and RctB, which have been...

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Identifiers

PMID: 18647828
DOI: 10.1073/pnas.0803904105
PMCID: PMC2492486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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