Article
[RtL164V, a mutation possibly associated with lamivudine resistant HBV].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Jul 2008
Wang Yu-ping, Yan Yan-sheng, Jiang Jia-ji
Abstract excerpt
OBJECTIVE: To study the efficacy of lamivudine treatment in chronic hepatitis B patients affected by structures of HBV P-genes. METHODS: P genes of HBV isolated from sera were amplified by means of one-step PCR and then sequenced. The sequences of the P-genes from responders, primary non-responders and rebounders were compared before and after their lamivudine treatments. RESULTS: (1) Among the primary...
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