Article
[The mutation patterns of HBV P gene and genotyping in patients with lanivudine-resistant chronic hepatitis B].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Oct 2011
Tang Jia-Liang, Zhou Jian-Kang
Abstract excerpt
OBJECTIVE: To analyze the mutation patters of HBV P gene and genotyping of heptitis B virus in patients with chronic hepatitis B (CHB) after the emergence of drug-resistance during lamivudine (LAM) therapy. METHODS: LAM-resistant mutations and genotype of HBV were dectected in patients with LAM-resistant CHB in our hospital from Sep. 2008 to June. 2010. RESULT: 107 patients had 8 mutation patterns. YMDD mutations...
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