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Article

[Mutations of HBV polymerase gene sequence in lamivudine-resistant chronic hepatitis B patients].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 May 2008

Wang Cheng, Sun Jian, Chen Jin-jun, Wang Zhan-hui, Hou Jin-lin

Abstract excerpt

OBJECTIVE: To explore the characteristics of mutation in HBV polymerase (P) gene reverse transcriptase region (RT region) in lamivudine-resistant chronic hepatitis B (CHB) patients. METHODS: This study involved 115 CHB patients who developed clinical resistance to lamivudine. Direct sequencing of the PCR products was used to detect lamivudine genotypic resistance. RESULTS: Lamivudine resistant mutation was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18504191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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