Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plaque dissociation of herpes simplex viruses: biochemical and biological characters of the viral variants.

Intervirology - 1 Jan 2000

Cassai E, Manservigi R, Corallini A, Terni M

Abstract excerpt

Polycaryocytogenic (P) and non-polycaryocytogenic, or aggregating (A), stable variants were selected from a herpes simplex virus type 1 (HSV-1) and from a herpes simplex virus type 2 (HSV 2) which had not been deliberately exposed to known mutagenic agents. The P variant of HSV-1 (FP) differed from the A variant (FA) in polypeptides and glycoprotein patterns, but no gross differences were evident between the two...

Topics

Cell Line
Cytopathogenic Effect, Viral
DNA, Viral
Genetic Variation
Glycoproteins
Hot Temperature
Neutralization Tests
Simplexvirus
Viral Plaque Assay
Viral Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 186433
DOI: 10.1159/000149476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-186433-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Plaque dissociation of herpes simplex viruses: biochemical and biological characters of the viral variants.PMID 186433Read ↗

Identification of syncytial mutations in a clinical isolate of herpes simplex virus 2.Semantic proximity Read ↗

Antigenic and genetic variation in cytopathic hepatitis A virus variants arising during persistent infection: evidence for genetic recombination.Semantic proximity Read ↗

Susceptibilities of herpes simplex viruses to penciclovir and acyclovir in eight cell lines.Semantic proximity Read ↗

A persistent infection in MDCK cells by an influenza type B virus.Semantic proximity Read ↗

Phenotypic characterization of antigenic hybrids of poliovirus.Semantic proximity Read ↗

Limited variability of glycoprotein gene sequences and neutralizing targets in herpes simplex virus type 2 isolates and stability on passage in cell culture.Semantic proximity Read ↗

In vitro selection of variants of herpes simplex virus type 1 which differ in cytopathic changes.Semantic proximity Read ↗

Characterization of glycoprotein C-negative mutants of herpes simplex virus type 1 isolated from a patient with keratitis.Semantic proximity Read ↗

Emergence of herpes simplex virus-1 syncytial variants with altered virulence for mice after selection with a natural carrageenan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.