Article
Characterization of glycoprotein C-negative mutants of herpes simplex virus type 1 isolated from a patient with keratitis.
Archives of virology - 1 Jan 1990
Hidaka Y, Sakuma S, Kumano Y, Minagawa H, Mori R
Abstract excerpt
Recently three strains of herpes simplex virus type 1 (HSV-1), which did not react with Micro Trak Herpes (Syva Co.), were isolated by us from a patient with recurrent herpetic keratitis. In this study we characterized these strains of HSV-1 and found them to be HSV-1 gC- mutants which are very r...
Topics
- Adult
- Animals
- Complement System Proteins
- DNA Restriction Enzymes
- DNA, Viral
- Electrophoresis, Polyacrylamide Gel
- Fluorescent Antibody Technique
- Humans
- Keratitis, Dendritic
- Male
- Mice
- Mice, Inbred BALB C
- Microbial Sensitivity Tests
- Mutation
- Simplexvirus
- Vero Cells
- Viral Envelope Proteins
- Viral Plaque Assay