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Article

Antigenic and genetic variation in cytopathic hepatitis A virus variants arising during persistent infection: evidence for genetic recombination.

Journal of virology - 1 Apr 1991

Lemon S M, Murphy P C, Shields P A, Ping L H, Feinstone S M, Cromeans T, Jansen R W

Abstract excerpt

Variants of hepatitis A virus (pHM175 virus) recovered from persistently infected green monkey kidney (BS-C-1) cells induced a cytopathic effect during serial passage in BS-C-1 or fetal rhesus kidney (FRhK-4) cells. Epitope-specific radioimmunofocus assays showed that this virus comprised two virion populations, one with altered antigenicity including neutralization resistance to monoclonal antibody K24F2, and...

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Identifiers

PMID: 1705995
DOI: 10.1128/JVI.65.4.2056-2065.1991
PMCID: PMC240056

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Source receipt: pubmed, retrieved 7 Sept 2026.

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