Article
Emergence of herpes simplex virus-1 syncytial variants with altered virulence for mice after selection with a natural carrageenan.
Sexually transmitted diseases - 1 Jun 2011
Mateu Cecilia G, Recalde Mercedes Perez, Artuso María C, Hermida Gladys, Linero Florencia N, Scolaro Luis A, Damonte Elsa B, Pujol Carlos A, Carlucci María J
Abstract excerpt
BACKGROUND: Antiviral therapy against herpes simplex virus based on sulfated polysaccharides, like carrageenans, represents a new alternative for genital herpes infections treatment and arises the concern about the appearance of resistant viral populations. METHODS: We characterized the F strain of herpes simplex virus-1 passaged in the presence of a natural carrageenan isolated from the red seaweed Gigartina...
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