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Article

Case-control study of oral and oropharyngeal cancer in whites and genetic variation in eight metabolic enzymes.

Head & neck - 1 Sept 2008

Buch Shama C, Nazar-Stewart Valle, Weissfeld Joel L, Romkes Marjorie

Abstract excerpt

BACKGROUND: Genetic variation in xenobiotic metabolizing enzymes may explain differing susceptibilities to the cancer causing effects of tobacco and alcohol. METHODS: We compared 203 oral squamous cell carcinoma cases and 416 controls for single nucleotide polymorphisms (SNPs) in 8 genes (CYP1A1, CYP2E1, MPO, mEH, GSTM1, GSTT1, GSTP1, and NAT2). Except for NAT2, genotype frequencies were similar in the 2 groups....

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Share to Arylamine N-Acetyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1A1

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Share to Gene Expression Regulation, Enzymologic

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Source

Open in PubMed Open full text

Identifiers

PMID: 18642288
DOI: 10.1002/hed.20867
PMCID: PMC3627181

Genes

NAT2
MPO
GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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