Alteration of the risk of pre-oral cancer and cancer in North Indian population by NAT1 and NAT2 polymorphisms genotypes and haplotypes.

doi:10.1007/s00405-021-06774-w

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Article

Alteration of the risk of pre-oral cancer and cancer in North Indian population by NAT1 and NAT2 polymorphisms genotypes and haplotypes.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Oct 2021

Nigam Kumud, Gupta Shalini, Gupta Om Prakash, Srivastav Ratnesh Kumar, Singh Saurabh Pratap, Sanyal Somali

Abstract excerpt

PURPOSE: The risk of oral cancer is strongly related to consumption of tobacco, smoking and drinking alcohol. N-acetyl transferases 1,2 are phase II metabolic enzymes, metabolize aryl and heterocyclic amines which are present in tobacco. NAT2 slows acetylator phenotype and the genotype is related...

Topics

Arylamine N-Acetyltransferase
Case-Control Studies
Genotype
Haplotypes
Humans
Isoenzymes
Mouth Neoplasms
Polymorphism, Genetic
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 33813602
DOI: 10.1007/s00405-021-06774-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-33813602-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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