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Article

An unlikely role for the NAT2 genotypes and haplotypes in the oral cancer of south Indians.

Archives of oral biology - 1 May 2012

Balaji Lakshmi, Krishna Balaji Singh, Bhaskar L V K S

Abstract excerpt

UNLABELLED: The arylamine N-acetyltransferase 2 (NAT2) enzyme detoxifies a wide spectrum of naturally occurring xenobiotics including carcinogens and drugs. Acetylation catalysed by the NAT2 is an important process in metabolic activation of arylamines to electrophilic intermediates that initiate carcinogenesis. Polymorphism in N-acetyltransferase 2 gene was reported to be associated with the susceptibility of...

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Identifiers

PMID: 22137356
DOI: 10.1016/j.archoralbio.2011.10.019

Genes

NAT2

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Related research

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Click a neighbor to travelStep 1 · 12 closest

An unlikely role for the NAT2 genotypes and haplotypes in the oral cancer of south Indians.PMID 22137356Read ↗

Alteration of the risk of pre-oral cancer and cancer in North Indian population by NAT1 and NAT2 polymorphisms genotypes and haplotypes.Semantic proximity Read ↗

Association study of NAT2 gene polymorphism and risk of oral cancer in Southern Punjab, Pakistan.Semantic proximity Read ↗

Role of arylamine N-acetyltransferase 1 and 2 (NAT1 and NAT2) genotypes in susceptibility to oral/pharyngeal and laryngeal cancers.Semantic proximity Read ↗

NAT2 polymorphisms with oral carcinoma susceptibility: a meta-analysis.Semantic proximity Read ↗

Association between polymorphisms at N-acetyltransferase 1 (NAT1) & risk of oral leukoplakia & cancer.Semantic proximity Read ↗

Association of genetic polymorphisms of N-acetyltransferase 2 and susceptibility to esophageal cancer in north Indian population.Semantic proximity Read ↗

Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms.Semantic proximity Read ↗

N-Acetyltransferase 2 polymorphisms, cigarette smoking and alcohol consumption, and oral squamous cell cancer risk.Semantic proximity Read ↗

Association of the cytochrome P450 and arylamine N-acetyltransferase gene polymorphisms with the incidence of head and neck cancer in Polish population.Semantic proximity Read ↗

N-acetyltransferase 2 gene polymorphisms are associated with susceptibility to cancer: a meta-analysis.Semantic proximity Read ↗

Association of arylamine N-acetyltransferases NAT1 and NAT2 genotypes to laryngeal cancer risk.Semantic proximity Read ↗

N-acetyltransferase 1 and 2 gene sequence variants and risk of head and neck cancer.Semantic proximity Read ↗

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