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Article

Pharmacokinetic interaction between pravastatin and olmesartan in relation to SLCO1B1 polymorphism.

Journal of human genetics - 1 Jan 2008

Suwannakul Suttasinee, Ieiri Ichiro, Kimura Miyuki, Kawabata Kiyoshi, Kusuhara Hiroyuki, Hirota Takeshi, Irie Shin, Sugiyama Yuichi, Higuchi Shun

Abstract excerpt

The impact of SLCO1B1 polymorphism on the pharmacokinetics of olmesartan and on the pharmacokinetic interaction between pravastatin and olmesartan was investigated. On day 1, ten healthy volunteers took an oral dose (10 mg) of pravastatin. After a 3-day washout period, each subject received olmesartan medoxomil (10 mg) for 3 days. On day 8, they received olmesartan medoxomil (10 mg) and pravastatin (10 mg)...

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Identifiers

PMID: 18641915
DOI: 10.1007/s10038-008-0324-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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