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Article

Development of a pharmacokinetic interaction model for co-administration of simvastatin and amlodipine.

Drug metabolism and pharmacokinetics - 1 Jan 2014

Son Hankil, Lee Donghwan, Lim Lay Ahyoung, Jang Seong Bok, Roh Hyerang, Park Kyungsoo

Abstract excerpt

A model for drug interaction between amlodipine and simvastatin was developed using concentration data obtained from a multiple-dose study consisting of single- and co-administration of amlodipine and simvastatin conducted in healthy Koreans. Amlodipine concentrations were assumed to influence th...

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PMID: 23965645
DOI: 10.2133/dmpk.dmpk-13-rg-053

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23965645-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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