Article
Lack of evidence for association of a UCH-L1 S18Y polymorphism with Parkinson's disease in a Han-Chinese population.
Neuroscience letters - 19 Sept 2008
Zhang Z-J, Burgunder J-M, An X-K, Wu Y, Chen W-J, Zhang J-H, Wang Y-C, Xu Y-M, Gou Y-R, Yuan G-G, Mao X-Y, Peng R
Abstract excerpt
Mutation in UCH-L1 has been reported as a rare cause of autosomal dominant Parkinson's disease (PD). A S18Y polymorphism in the same gene has been associated with sporadic PD. We investigated the frequency of this polymorphism among the Han-Chinese ethnic population in a case-control study. A total of 600 patients with PD and 334 unrelated healthy controls were genotyped using PCR-restriction fragment length...
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