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Article

No genetic association of the ubiquitin carboxy-terminal hydrolase-L1 gene S18Y polymorphism with familial Parkinson's disease.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2001

Levecque C, Destée A, Mouroux V, Becquet E, Defebvre L, Amouyel P, Chartier-Harlin M C

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative disorder for which genetic susceptibility has been documented in sporadic and familial cases. Recently, a polymorphism located in exon 3 at codon 18 (S18Y) of the Ubiquitin Carboxy-terminal Hydrolase-L1 (UCH-L1) gene has been associated with the disease in 2 populations of German origin and also in a Japanese population. We tested the impact of this polymorphism in...

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PMID: 11716150
DOI: 10.1007/s007020170017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No genetic association of the ubiquitin carboxy-terminal hydrolase-L1 gene S18Y polymorphism with familial Parkinson's disease.PMID 11716150Read ↗

Case-control study of the UCH-L1 S18Y variant in sporadic Parkinson's disease in the Chinese population.Semantic proximity Read ↗

Case-control study of the ubiquitin carboxy-terminal hydrolase L1 gene in Parkinson's disease.Semantic proximity Read ↗

The ubiquitin carboxy-terminal hydrolase-L1 gene S18Y polymorphism does not confer protection against idiopathic Parkinson's disease.Semantic proximity Read ↗

A polymorphic variation of serine to tyrosine at codon 18 in the ubiquitin C-terminal hydrolase-L1 gene is associated with a reduced risk of sporadic Parkinson's disease in a Japanese population.Semantic proximity Read ↗

Lack of evidence for association of a UCH-L1 S18Y polymorphism with Parkinson's disease in a Han-Chinese population.Semantic proximity Read ↗

UCHL-1 is not a Parkinson's disease susceptibility gene.Semantic proximity Read ↗

Association between ubiquitin carboxy-terminal hydrolase-L1 S18Y variant and risk of Parkinson's disease: the impact of ethnicity and onset age.Semantic proximity Read ↗

S18Y in ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) associated with decreased risk of Parkinson's disease in Sweden.Semantic proximity Read ↗

The UCHL1 S18Y polymorphism and Parkinson's disease in a Japanese population.Semantic proximity Read ↗

Low frequency of pathogenic mutations in the ubiquitin carboxy-terminal hydrolase gene in familial Parkinson's disease.Semantic proximity Read ↗

Lack of association between ubiquitin carboxy-terminal hydrolase L1 gene polymorphism and PDSemantic proximity Read ↗

Genetic association between Ubiquitin Carboxy-terminal Hydrolase-L1 gene S18Y polymorphism and sporadic Alzheimer's disease in a Chinese Han population.Semantic proximity Read ↗

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