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Article

The retinoblastoma tumour suppressor in development and cancer.

Nature reviews. Cancer - 1 Dec 2002

Classon Marie, Harlow Ed

Abstract excerpt

Since its discovery, the retinoblastoma (RB) tumour-suppressor protein has been a focal point of cancer research. Accumulating evidence indicates a complex role for RB in cell proliferation, differentiation and survival. To further complicate matters, proteins that are related to RB have redundant as well as antagonistic functions. Recent studies of knockout mice and cells that lack one or more of these proteins...

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Identifiers

PMID: 12459729
DOI: 10.1038/nrc950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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