Article
The genetic analysis of cancer.
Journal of internal medicine - 1 Jun 1998
Pearson P L, Van der Luijt R B
Abstract excerpt
During the past two decades an overwhelming amount of knowledge has been acquired on the molecular genetics of human cancer. It is now evident that cancer is essentially a genetic disease, arising from inherited and/or somatically acquired mutations at different genetic loci, and that tumourigenesis is a multistep process. Gene mapping studies of inherited cancer syndromes have resulted in the identification of...
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