Article
The molecular genetics of retinoblastoma.
Cancer surveys - 1 Jan 1990
Goodrich D W, Lee W H
Abstract excerpt
Retinoblastoma is a potentially hereditary cancer. Refinement of the genetic and epidemiological analysis of the disease has uncovered two distinct classes of retinoblastoma. Sporadic retinoblastoma is generally unilateral and unifocal, and is diagnosed at the late age of about two years. A few of these sporadic cases are probably due to a germ cell mutation inherited from a parent and hence can be classified as...
Topics
- Chromosome Mapping
- Cloning, Molecular
- Eye Neoplasms
- Gene Expression Regulation, Neoplastic
- Genes, Retinoblastoma
- Humans
- Mutation
- Retinoblastoma