Article
Oncogenes and cancer: clinical applications.
Cleveland Clinic journal of medicine - 1 Jan 2000
Fishleder A J
Abstract excerpt
Oncogenes are aberrant forms of proto-oncogenes, which are normal cellular genes that participate in cell growth and development; proto-oncogenes contribute to tumor formation when mutations or chromosomal translocation cause them to escape normal controls. Anti-oncogenes, also involved in neoplasm development, normally participate in inhibition of cell growth and proliferation; they become tumorigenic when...
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