Article
From chimney sweeps to oncogenes: the quest for the causes of cancer.
Radiology - 1 May 1991
Hall E J
Abstract excerpt
Over the past 200 years, a bewildering array of chemical, physical, and viral agents has been identified that can cause cancer, but the mechanisms involved are only now becoming clear. In the leukemias and lymphomas, it appears that the activation of cellular oncogenes is important. The genes involved are present in all normal cells and are often associated with cell growth and regulation. When activated, they...
Topics
- Animals
- Cell Transformation, Neoplastic
- Chromosome Aberrations
- Gene Expression Regulation, Neoplastic
- Genes, Retinoblastoma
- Genes, Suppressor
- Humans
- Hybrid Cells
- Mutation
- Neoplasms
- Neoplasms, Experimental