Article
No evidence of association between frontotemporal dementia and major European mtDNA haplogroups.
European journal of neurology - 1 Sept 2008
Rose G, Longo T, Maletta R, Passarino G, Bruni A C, De Benedictis G
Abstract excerpt
BACKGROUND AND PURPOSE: Mitochondrial DNA (mtDNA) inherited variability (haplogroup/sub-haplogroup) is currently emerging as not being neutral with respect to several complex traits like neurodegenerative diseases. Here we investigated the association of European mtDNA haplogroups/sub-haplogroups with frontotemporal dementia (FTD). METHOD AND RESULTS: A case-control study was carried out on 114 patients with FTD...
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