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Article

The complex evolutionary dynamics of Hsp70s: a genomic and functional perspective.

Genome biology and evolution - 1 Jan 2013

Kominek Jacek, Marszalek Jaroslaw, Neuvéglise Cécile, Craig Elizabeth A, Williams Barry L

Abstract excerpt

Hsp70 molecular chaperones are ubiquitous. By preventing aggregation, promoting folding, and regulating degradation, Hsp70s are major factors in the ability of cells to maintain proteostasis. Despite a wealth of functional information, little is understood about the evolutionary dynamics of Hsp70s. We undertook an analysis of Hsp70s in the fungal clade Ascomycota. Using the well-characterized 14 Hsp70s of...

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PMID: 24277689
DOI: 10.1093/gbe/evt192
PMCID: PMC3879978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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