Article

The Role of Non-Canonical Hsp70s (Hsp110/Grp170) in Cancer

2020-12-17

Abstract excerpt

Although cancers account for over 16% of all global deaths annually, at present, no reliable therapies exist for most types of the disease. As protein folding facilitators, heat shock proteins (Hsps) play an important role in cancer development. Not surprisingly, Hsps are among leading anticancer drug targets. Generally, Hsp70s are divided into two main subtypes: canonical Hsp70 (E. coli Hsp70/DnaK homologues) and...

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Literature Corpus work: 75c281a0-870e-562f-93ed-9ee72dd9c651
DOI: 10.20944/preprints202012.0434.v1

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