Article
Mitochondrial HSP70 Chaperone System-The Influence of Post-Translational Modifications and Involvement in Human Diseases.
International journal of molecular sciences - 28 Jul 2021
Havalová Henrieta, Ondrovičová Gabriela, Keresztesová Barbora, Bauer Jacob A, Pevala Vladimír, Kutejová Eva, Kunová Nina
Abstract excerpt
Since their discovery, heat shock proteins (HSPs) have been identified in all domains of life, which demonstrates their importance and conserved functional role in maintaining protein homeostasis. Mitochondria possess several members of the major HSP sub-families that perform essential tasks for keeping the organelle in a fully functional and healthy state. In humans, the mitochondrial HSP70 chaperone system...
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