Article
Intracellular Protozoan Parasites of Humans: The Role of Molecular Chaperones in Development and Pathogenesis
31 Jan 2011
Abstract excerpt
Certain kinetoplastid (Leishmania spp. and Tryapnosoma cruzi) and apicomplexan parasites (Plasmodium falciparum and Toxoplasma gondii) are capable of invading human cells as part of their pathology. These parasites appear to have evolved a relatively expanded or diverse complement of genes encoding molecular chaperones. The gene families encoding heat shock protein 90 (Hsp90) and heat shock protein 70 (Hsp70)...
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