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Article

Caveolin-1 interacts with a lipid raft-associated population of fatty acid synthase.

Cell cycle (Georgetown, Tex.) - 15 Jul 2008

Di Vizio Dolores, Adam Rosalyn M, Kim Jayoung, Kim Robert, Sotgia Federica, Williams Terence, Demichelis Francesca, Solomon Keith R, Loda Massimo, Rubin Mark A, Lisanti Michael P, Freeman Michael R

Abstract excerpt

Fatty Acid Synthase (FASN), a cytoplasmic biosynthetic enzyme, is the major source of long-chain fatty acids, particularly palmitate. Caveolin-1 (Cav-1) is a palmitoylated lipid raft protein that plays a key role in signal transduction and cholesterol transport. Both proteins have been implicated...

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Source

Identifiers

PMID: 18635971
DOI: 10.4161/cc.7.14.6475

Genes

FASN
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18635971-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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