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Article

Oleic acid promotes prostate cancer malignant phenotype via the G protein-coupled receptor FFA1/GPR40.

Journal of cellular physiology - 1 Sept 2018

Liotti Antonietta, Cosimato Vincenzo, Mirra Paola, Calì Gaetano, Conza Domenico, Secondo Agnese, Luongo Gelsomina, Terracciano Daniela, Formisano Pietro, Beguinot Francesco, Insabato Luigi, Ulianich Luca

Abstract excerpt

Prostate cancer (PCa) is the most commonly diagnosed malignancy in men and the second leading cause of cancer-related death in industrialized countries. Epidemiologic evidence suggests that obesity promotes aggressive PCa. Recently, a family of Free Fatty Acid (FFA) receptors (FFARs) has been identified and reported to affect several crucial biological functions of tumor cells such as proliferation, invasiveness,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29663374
DOI: 10.1002/jcp.26572
PMCID: PMC13482116

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