Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Impact of single nucleotide polymorphisms in glutathione S transferase gene GSTP1 in the treatment with oxaliplatin based chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jul 2008

Oki Eiji, Kakeji Yoshihiro, Ohgaki Kippei, Saeki Kohji, Morita Masaru, Emi Yasunori, Maehara Yoshihiko

Abstract excerpt

Oxaliplatin has been the main treatment of choice in colorectal cancer in advanced settings. However, cellular mechanisms for the uptake, intracellular distribution and efflux of oxaliplatin are unknown. GST(glutathione S transferase)is member of a superfamily of metabolic enzymes that play an im...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to GSTP1 gene
Share to Glutathione Transferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms

Share to Organoplatinum Compounds

Share to Oxaliplatin

Share to Polymorphism, Single Nucleotide

Share to Substrate Specificity

Source

Identifiers

PMID: 18633248

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18633248-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Impact of single nucleotide polymorphisms in glutathione S transferase gene GSTP1 in the treatment with oxaliplatin based chemotherapy].PMID 18633248Read ↗

XRCC1 and GSTP1 polymorphisms and prognosis of oxaliplatin-based chemotherapy in colorectal cancer: a meta-analysis.Semantic proximity Read ↗

GSTM1 and GSTP1 Polymorphisms Affect Outcome in Colorectal Adenocarcinoma.Semantic proximity Read ↗

[Recent developments of pharmacogenomics in the treatment of colorectal cancers].Semantic proximity Read ↗

Platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma: glutathione S-transferase genetic polymorphisms as predictive biomarkers of disease outcome.Semantic proximity Read ↗

Polymorphism and transcriptional regulation of GSTP1 in cancer and other human diseases.Semantic proximity Read ↗

Pharmacology of oxaliplatin and the use of pharmacogenomics to individualize therapy.Semantic proximity Read ↗

Glutathione S-transferases: an overview in cancer research.Semantic proximity Read ↗

[Advances in research on the association between single nucleotide polymorphisms of the DNA repair genes and resistance to platinum-based chemotherapy].Semantic proximity Read ↗

[Single nucleotide polymorphism analysis in the GSTP1 and ABCC2 genes about neuropathy by the Oxaliplatin].Semantic proximity Read ↗

GSTP1 and cancer: Expression, methylation, polymorphisms and signaling (Review).Semantic proximity Read ↗

GSTP1, ERCC1 and ERCC2 polymorphisms, expression and clinical outcome of oxaliplatin-based adjuvant chemotherapy in colorectal cancer in Chinese population.Semantic proximity Read ↗

Glutathione Transferase P1: Potential Therapeutic Target in Ovarian CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.