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Article

[Single nucleotide polymorphism analysis in the GSTP1 and ABCC2 genes about neuropathy by the Oxaliplatin].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Dec 2008

Mori Yasuharu, Katsumata Kenji, Tsuchida Akihiko, Aoki Tatsuya

Abstract excerpt

The appearance of neuropathy that is a harmful phenomenon of Oxaliplatin, the key drug of FOLFOX, is strongly concerned in individual pharmacological variability. Further more, the frequency of neuropathy appearance was reported to be 74.3%. In this study, we examined a correlation between GSTP1(342G>A)and ABCC2(1249G>A)of genetic polymorphism. The mean FOLFOX drug dosage was 8.6 times. The first, second and...

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Source

Identifiers

PMID: 19098406

Genes

ABCC2
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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