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Article

Analysis of molecular pathways in sporadic neuroendocrine tumors of the gastro‐entero‐pancreatic system

3 Feb 2007

Abstract excerpt

Little is known about the molecular pathogenesis of neuroendocrine tumors (NET) of the gastro-entero-pancreatic (GEP) system. We analyzed genetic and epigenetic alterations as well as the CpG island methylator phenotype (CIMP). The study comprised 118 well-differentiated fore- and mid-gut GEP-NET from 71 patients. In addition to loss of heterozygosity (LOH), microsatellite instability (MSI) and the methylation...

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PMID: 17278096
DOI: 10.1002/ijc.22569

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