Article
DNA repair gene XRCC3 polymorphisms and bladder cancer risk: a meta-analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2014
Peng Qiliu, Mo Cuiju, Tang Weizhong, Chen Zhiping, Li Ruolin, Zhai Limin, Yang Shi, Wu Junrong, Sui Jingzhe, Li Shan, Qin Xue
Abstract excerpt
The X-ray repair cross-complementing group 3 (XRCC3) in homologous recombination repair (HRR) pathway plays a vital role in DNA double-strand break repair (DSBR). Variants in the XRCC3 gene might result in altered protein structure or function which may influence DSBR efficiency and lead to cancer. Numerous epidemiological studies have been conducted to evaluate the association between XRCC3 polymorphisms and...
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