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Article

Epigenotyping in peripheral blood cell DNA and breast cancer risk: a proof of principle study.

PloS one - 16 Jul 2008

Widschwendter Martin, Apostolidou Sophia, Raum Elke, Rothenbacher Dietrich, Fiegl Heidi, Menon Usha, Stegmaier Christa, Jacobs Ian J, Brenner Hermann

Abstract excerpt

BACKGROUND: Epigenetic changes are emerging as one of the most important events in carcinogenesis. Two alterations in the pattern of DNA methylation in breast cancer (BC) have been previously reported; active estrogen receptor-alpha (ER-alpha) is associated with decreased methylation of ER-alpha target (ERT) genes, and polycomb group target (PCGT) genes are more likely than other genes to have promoter DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18628976
DOI: 10.1371/journal.pone.0002656
PMCID: PMC2442168

Genes

GDNF
MYOD1
PITX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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