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Article

Penetrance analysis of the PALB2 c.1592delT founder mutation.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2008

Erkko Hannele, Dowty James G, Nikkilä Jenni, Syrjäkoski Kirsi, Mannermaa Arto, Pylkäs Katri, Southey Melissa C, Holli Kaija, Kallioniemi Anne, Jukkola-Vuorinen Arja, Kataja Vesa, Kosma Veli-Matti, Xia Bing, Livingston David M, Winqvist Robert, Hopper John L

Abstract excerpt

PURPOSE: PALB2 is a recently identified breast cancer susceptibility gene. We have previously identified in the Finnish population a PALB2 c.1592delT founder truncation mutation that is associated with an increased risk of breast cancer. In the present study, we wanted to assess in more detail th...

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Source

Identifiers

PMID: 18628482
DOI: 10.1158/1078-0432.CCR-08-0210

Genes

PALB2
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18628482-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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