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Article

PALB2 variants in hereditary and unselected Finnish prostate cancer cases.

Journal of negative results in biomedicine - 15 Dec 2009

Pakkanen Sanna, Wahlfors Tiina, Siltanen Sanna, Patrikainen Mimmi, Matikainen Mika P, Tammela Teuvo L J, Schleutker Johanna

Abstract excerpt

BACKGROUND: PALB2 1592delT mutation is associated with increased breast cancer and suggestive prostate cancer (PRCA) risk in Finland. In this study we wanted to assess if any other PALB2 variants associate to increased PRCA risk and clinically describe patients with formerly found PALB2 1592delT...

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Source

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Identifiers

PMID: 20003494
DOI: 10.1186/1477-5751-8-12
PMCID: PMC2806404

Genes

PALB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20003494-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PALB2 variants in hereditary and unselected Finnish prostate cancer cases.PMID 20003494Read ↗

A recurrent mutation in PALB2 in Finnish cancer families.Semantic proximity Read ↗

Analysis of the gene coding for the BRCA2-interacting protein PALB2 in hereditary prostate cancer.Semantic proximity Read ↗

Contribution of germline PALB2 variants to an unselected and prospectively registered pancreatic cancer patient cohort in Pakistan.Semantic proximity Read ↗

PALB2 mutations and prostate cancer risk and survival.Semantic proximity Read ↗

PALB2 and the risks for cancer: implications for clinical care.Semantic proximity Read ↗

Evaluation of the need for routine clinical testing of PALB2 c.1592delT mutation in BRCA negative Northern Finnish breast cancer families.Semantic proximity Read ↗

BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients.Semantic proximity Read ↗

Genetics risk assessment of PALB2 polymorphism (rs249954 and rs152451) with breast cancer susceptibility among the Pashtun population of Khyber Pakhtunkhwa, PakistanSemantic proximity Read ↗

Heterozygous PALB2 c.1592delT mutation channels DNA double-strand break repair into error-prone pathways in breast cancer patients.Semantic proximity Read ↗

Mutation analysis of PALB2 gene in French breast cancer families.Semantic proximity Read ↗

Contribution of germline mutations in the BRCA and PALB2 genes to pancreatic cancer in Italy.Semantic proximity Read ↗

Penetrance analysis of the PALB2 c.1592delT founder mutation.Semantic proximity Read ↗

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