Article
Evaluation of BRCA1 and BRCA2 mutations and risk-prediction models in a typical Asian country (Malaysia) with a relatively low incidence of breast cancer.
Breast cancer research : BCR - 1 Jan 2008
Thirthagiri E, Lee S Y, Kang P, Lee D S, Toh G T, Selamat S, Yoon S-Y, Taib N A Mohd, Thong M K, Yip C H, Teo S H
Abstract excerpt
INTRODUCTION: The cost of genetic testing and the limited knowledge about the BRCA1 and BRCA2 genes in different ethnic groups has limited its availability in medium- and low-resource countries, including Malaysia. In addition, the applicability of many risk-assessment tools, such as the Manchester Scoring System and BOADICEA (Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm)...
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