Article
Mars promotes dTACC dephosphorylation on mitotic spindles to ensure spindle stability.
The Journal of cell biology - 14 Jul 2008
Tan Shengjiang, Lyulcheva Ekaterina, Dean Jon, Bennett Daimark
Abstract excerpt
Microtubule-associated proteins (MAPs) ensure the fidelity of chromosome segregation by controlling microtubule (MT) dynamics and mitotic spindle stability. However, many aspects of MAP function and regulation are poorly understood in a developmental context. We show that mars, which encodes a Drosophila melanogaster member of the hepatoma up-regulated protein family of MAPs, is essential for MT stabilization...
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