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Article

MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity.

The Journal of cell biology - 27 May 2002

Maiato Helder, Sampaio Paula, Lemos Catarina L, Findlay John, Carmena Mar, Earnshaw William C, Sunkel Claudio E

Abstract excerpt

Multiple asters (MAST)/Orbit is a member of a new family of nonmotor microtubule-associated proteins that has been previously shown to be required for the organization of the mitotic spindle. Here we provide evidence that MAST/Orbit is required for functional kinetochore attachment, chromosome congression, and the maintenance of spindle bipolarity. In vivo analysis of Drosophila mast mutant embryos undergoing...

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Identifiers

PMID: 12034769
DOI: 10.1083/jcb.200201101
PMCID: PMC2173411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity.PMID 12034769Read ↗

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