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Article

Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis.

Nature genetics - 1 Aug 2008

Miyamoto Yoshinari, Shi Dongquan, Nakajima Masahiro, Ozaki Kouichi, Sudo Akihiro, Kotani Akihiro, Uchida Atsumasa, Tanaka Toshihiro, Fukui Naoshi, Tsunoda Tatsuhiko, Takahashi Atsushi, Nakamura Yusuke, Jiang Qing, Ikegawa Shiro

Abstract excerpt

Susceptibility to osteoarthritis, the most common human arthritis, is known to be influenced by genetic factors. Through a genome-wide association study using approximately 100,000 SNPs, we have identified a previously unknown gene on chromosome 3p24.3, DVWA, which is associated with susceptibility to knee osteoarthritis. Expressed specifically in cartilage, DVWA encodes a 276-amino-acid protein with two regions...

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PMID: 18622395
DOI: 10.1038/ng.176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis.PMID 18622395Read ↗

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Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations.Semantic proximity Read ↗

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