Article
Genetic variants from lipid-related pathways and risk for incident myocardial infarction.
PloS one - 1 Jan 2013
Song Ci, Pedersen Nancy L, Reynolds Chandra A, Sabater-Lleal Maria, Kanoni Stavroula, Willenborg Christina, Syvänen Ann-Christine, Watkins Hugh, Hamsten Anders, Prince Jonathan A, Ingelsson Erik
Abstract excerpt
BACKGROUND: Circulating lipids levels, as well as several familial lipid metabolism disorders, are strongly associated with initiation and progression of atherosclerosis and incidence of myocardial infarction (MI). OBJECTIVES: We hypothesized that genetic variants associated with circulating lipid levels would also be associated with MI incidence, and have tested this in three independent samples. SETTING AND...
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