Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cardiac cholinergic NO-cGMP signaling following acute myocardial infarction and nNOS gene transfer.

American journal of physiology. Heart and circulatory physiology - 1 Sept 2008

Dawson T A, Li D, Woodward T, Barber Z, Wang L, Paterson D J

Abstract excerpt

Myocardial infarction (MI) is associated with oxidative stress, which may cause cardiac autonomic impairment. We tested the hypothesis that acute MI disrupts cardiac cholinergic signaling by impairing nitric oxide (NO)-cGMP modulation of acetylcholine (ACh) release and whether the restoration of this pathway following cardiac neuronal NO synthase (nNOS) gene transfer had any bearing on the neural phenotype....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcholine
Share to Biopterins
Share to Cyclic GMP

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Transfer Techniques

Share to Guinea Pigs

Share to Nitric Oxide

Share to Nitric Oxide Synthase Type I

Source

Open in PubMed Open full text

Identifiers

PMID: 18621854
DOI: 10.1152/ajpheart.00492.2008
PMCID: PMC2544496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cardiac cholinergic NO-cGMP signaling following acute myocardial infarction and nNOS gene transfer.PMID 18621854Read ↗

Myocardial Infarction Causes Transient Cholinergic Transdifferentiation of Cardiac Sympathetic Nerves via gp130.Semantic proximity Read ↗

Deterioration of cardiac function after acute myocardial infarction is prevented by transplantation of modified endothelial progenitor cells overexpressing endothelial NO synthases.Semantic proximity Read ↗

Cardiomyocyte-specific overexpression of nitric oxide synthase 3: impact on left ventricular function and myocardial infarction.Semantic proximity Read ↗

Nitric Oxide Synthase Gene Therapy for Cardiovascular DiseaseSemantic proximity Read ↗

S-Nitrosoglutathione Reductase Deficiency Enhances the Proliferative Expansion of Adult Heart Progenitors and Myocytes Post Myocardial Infarction.Semantic proximity Read ↗

Cholinergic Stimulation Exerts Cardioprotective Effects and Alleviates Renal Inflammatory Responses after Acute Myocardial Infarction in Spontaneous Hypertensive Rats (SHRs)Semantic proximity Read ↗

Cardiomyopathy in dystrophin-deficient hearts is prevented by expression of a neuronal nitric oxide synthase transgene in the myocardiumSemantic proximity Read ↗

Remodeling of the cardiac pacemaker L-type calcium current and its beta-adrenergic responsiveness in hypertension after neuronal NO synthase gene transfer.Semantic proximity Read ↗

Inhibition of iNOS protects the aging heart against beta-adrenergic receptor stimulation-induced cardiac dysfunction and myocardial ischemic injury.Semantic proximity Read ↗

Chronic myocardial infarction induces phenotypic and functional remodeling in the guinea pig cardiac plexus.Semantic proximity Read ↗

Endothelial nitric oxide synthase limits left ventricular remodeling after myocardial infarction in mice.Semantic proximity Read ↗

Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocardial infarction in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.