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Article

Inhibition of iNOS protects the aging heart against beta-adrenergic receptor stimulation-induced cardiac dysfunction and myocardial ischemic injury.

The Journal of surgical research - 1 Mar 2006

Li Dianyuan, Qu Yan, Tao Ling, Liu Huirong, Hu Aihua, Gao Feng, Sharifi-Azad Said, Grunwald Zvi, Ma Xin-Liang, Sun Jian-Zhong

Abstract excerpt

BACKGROUND: beta-adrenergic receptor (AR) and aging are two major contributors to pathogenesis of perioperative myocardial ischemia and infarction. This study compared the response to beta-AR stimulation in the young and aging heart and examined the role of inducible nitric oxide synthase (iNOS) in aging related myocardial ischemic injury and its relation to beta-AR stimulation. MATERIAL AND METHODS: Isolated...

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Share to Adrenergic beta-Agonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16154595
DOI: 10.1016/j.jss.2005.06.038

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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