Article
Chronic myocardial infarction induces phenotypic and functional remodeling in the guinea pig cardiac plexus.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Dec 2008
Hardwick Jean C, Southerland E Marie, Ardell Jeffrey L
Abstract excerpt
Chronic myocardial infarction (CMI) is associated with remodeling of the ventricle and evokes adaption in the cardiac neurohumoral control systems. To evaluate the remodeling of the intrinsic cardiac nervous system following myocardial infarction, the dorsal descending coronary artery was ligated in the guinea pig heart and the animals were allowed to recover for 7-9 wk. Thereafter, atrial neurons of the...
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