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Article

The TNFalpha gene relates to clinical phenotype in alpha-1-antitrypsin deficiency.

Respiratory research - 11 Jul 2008

Wood Alice M, Simmonds Matthew J, Bayley Darren L, Newby Paul R, Gough Stephen C, Stockley Robert A

Abstract excerpt

BACKGROUND: Genetic variation may underlie phenotypic variation in chronic obstructive pulmonary disease (COPD) in subjects with and without alpha 1 antitrypsin deficiency (AATD). Genotype specific sub-phenotypes are likely and may underlie the poor replication of previous genetic studies. This s...

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Share to alpha 1-Antitrypsin
Share to alpha 1-Antitrypsin Deficiency
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Share to Pulmonary Disease, Chronic Obstructive

Share to Tumor Necrosis Factor-alpha

Source

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Identifiers

PMID: 18620570
DOI: 10.1186/1465-9921-9-52
PMCID: PMC2478658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18620570-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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